Settings for your cutting machine, whether CNC or laser, will vary depending on your machine, the specific paper stock you are using and other factors.
The paper I used for my cards was 0.014″ thick 105lb cover stock.
On the Glowforge, I used a speed of 500 and power of 72 for the cut lines and a power of 18 for the mountain fold lines. I scored the valley fold lines on the back by hand with a craft knife. If you are a Glowforge user, you likely have some experience dialing in settings for a particular material. I color-coded the file so that the GFUI will separate and order the operations on import.
27 July 2019 update: I’m seeing less smoke deposition with lower power and slower speed. I have switched to using 250 speed and 36 power.
My settings for each operation for the Gazelle cutter are in the MTC file as layer descriptions (D is depth setting on my adjustable blade holder, V is velocity and F is force). Those will probably be mostly useless unless you are also using a Gazelle cutter with an adjustable blade holder. If you are a craft cutter user, you are likely used to sorting out settings for a given stock. The layers are in the order you should cut them. The last two layers are the backing card (one score and the cuts).